Nathan Thomas Hopkins (October 27, 1852 - February 11, 1927) was a U.S. Representative from Kentucky.
Born in Ashe County, North Carolina, Hopkins moved to Pike County, Kentucky. He attended the common schools. He engaged in agricultural pursuits. Ordained to the ministry in the Baptist Church in 1876 and actively engaged in ministerial work for half a century. County tax assessor of Floyd County from 1878 to 1890. He served as member of the North Carolina House of Representatives from 1893 to 1894 and 1923-1924. He successfully contested as a Republican the election of Joseph M. Kendall to the Fifty-fourth Congress (February 18, 1897-March 3, 1897). Merchant, timberman, lumberman, farmer in Pike County, Kentucky. He was an unsuccessful candidate for election to the Fifty-seventh Congress in 1900. He engaged in agricultural pursuits near Yeager, Kentucky. He died in Pikesville, Kentucky, February 11, 1927. He was interred in Potter Cemetery, Yeager, Kentucky.